Scott,
Glad you're in love with the F50, that's one hell of a guitar.
Sugar,
I'm like you........always just snatched 'em all off and stuck 'em on. The only reason that I can see that you would use all of these other methods is to hold equal tension on everything.....saddle, bridge, neck, top, etc. The other thing, I believe it was Terry Lynn Hall that mentioned it......I have a D55 that HAD a saddle that had a high spot in it. Since put a new bone saddle in it and cleaned the slot. On that one, if you weren't careful to maintain pretty equal pressure, you could conceivably cock the saddle in the slot. I would think with uneven pressure on the saddle, strings on one end of the saddle could project and sustain longer and louder than the other end. Nothing scientific to base that on, just my opinion.
Again, I've always pulled them all and stuck them back on, but the Guild owner's manual does tell you to change them one at a time. I would suspect for the reasons listed.
West