Run-out rarely affects the sound of a guitar -- it's mainly cosmetic.
Also, run-out shouldn't be confused with the normal light-reflecting properties of a book-matched top. The two halves of a book-matched top will always reflect light differently because the grain runs in opposite directions. That's why if you're removing a bridge you want to go under the edge of the bridge, with your "spatula" tool, from the lower-bout side of one half and from the upper-bout side of the other half, so you're working WITH the grain, not against it.
Not crazy about this particular 'burst, but if the guitar sounds and plays great, and the price was right (this one's more than I'd consider paying), the look of the look of the 'burst wouldn't prevent me buying it at all.
Looks, for me, are secondary. The soul of a guitar is how it sounds.