As long as they come off and it's temporary, put 'em on and see! I like guitars to be original. My Breedlove has the tiniest little dots that you can hardly see, but the ebony is so beautiful I don't even care. It's the side dot markers that I use for guidance when I'm all over the fretboard, not any inlays. My guitars with big, beautiful inlays going on..... I don't even see them when I'm playing. They're more for the audience or me when I'm just LOOKING at the guitar.
You didn't say what guitar you're considering doing this on...... makes a difference, I think.