That said, I would be much more interested in innovation in the NS line than more re-imagining. The Orpheum is the acoustic that Guild might have made in the 1930's. What electric would Guild have made in the 90's if they had to compete with Fender rather than being owned by Fender? Was there a "Gibson-killer" that never left the drawing board? That is what I would like to see next in the NS line especially if it does not compete head to head with something in the used or vintage market that also has Guild on the headstock.
I think innovation is vastly overrated. The most popular guitars out there, to this day, are strats, teles, and Les Pauls. Save for a couple of small details, most of the current ones are pretty dang close to the original 1950's versions. I'll go further than that : half of the current electric guitar market are vintage inspired, reissued, vintage mash-up, brand new but reliced to look 40 yrs old guitars.
What could you do to a M-75 or a X175 that would make it a more relevant/interesting guitar? Put locking tuners on it? Give it those awful Gibson self-tuning robo tuners? Build a USB port, a camera and a phone into it? A lot of those things would make them more dated in five years than one of those Casio midi/synth strats looks now.
Being the roots-rock musician I am, with a taste for vintage guitars, I think it's fantastic they went the extra mile with the NS range and tooled up for Franz pickups, mini humbuckers, Full size Guild 'buckers, Hagstrom bass pickups, harp tailpieces, etc..... My remarks in earlier in this thread are about - yes, more of that please, those very very distinctly Guild things, but better quality. Have those pickups made by Fralin or Duncan or Lollar instead of by the cheapest bid from a Korean factory. Finish the guitars in nitro, do whatever it takes to get them closer to the real thing. I'm happy with how geeky a reissue I can get now for $1000, but I think I'd gladly pay about twice that for a guitar that sounds and feels even closer to my oldies. My NS guitar is a backup guitar now, but if it was just 50% closer to my oldies, I'd leave the oldies at home more than half the time.
The innovation bit : if that means making those guitars more generic with Gibson style hardware and pickups, or building a Guild branded super strat like we saw in the 80's, I'd see that as a step backwards, not innovation.